A "Clean Boot" procedure may fix this issue.

If you are running Windows 98/98se/ME:
1. Go to "Start", choose "Run", and type MSCONFIG in the "Open" box.
2. Click "OK". The System Configuration Utility should open.
3. On the "General" tab move the radio button to "Selective Startup"
and remove the check marks from everything EXCEPT "Process
System.ini file".
4. Click on "Apply", and then click on "OK".
5. A message stating "You must restart your computer before the new
settings will take effect. Do you want to restart your computer
now?" will open. Click on "Yes". The machine will reboot.

If the problem/event is still there, then Windows itself may be damaged. If it is gone, go back into the MSCONFIG program and click the Startup tab. Check back one or two items at a time and click Apply and Ok and reboot.

When the problem or event returns, then the last item(s) checked are the cause and they can be removed or reinstalled.

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Also,

Go to the Start button at the bottom of your screen, do a right mouse click and select explore.
On the left hand side of the screen you will see Start Menu highlighted in blue. Under Start Menu you should see a programs folder with a + next to it.
Click on the + to expand the folder.
On the expanded menu you will see a Startup folder. Click on it to select it.
If there are any icons on the right side of the screen, select and delete them.
These programs open and run everytime you start up and run in the background even through you have not opened them yourself.

Hi!
I am currently using this technique to troubleshoot a problem with my XPS T450. Everything seems okay with only the system.ini loading, but when I added the config.sys, my problem returned. What do I do now? Thanks!
Steve