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The B110 uses a Dell custom motherboard with a Dell proprietary and undocumented front panel connection.
If you want to use a motherboard with SATA on it you would have to build a new PC. Very little if anything from the B110 would be useable on a new motherboard.
The B110 was sold by Dell as a low price, "entry level" PC.
Inspiron 16 5630 Laptop and WD22TB4 Docking StationSelf-built desktop for recording studio applicationshesagordie
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Posted May 8th, 2011 08:00
Does anyone know if there is a sata motherboard upgrade available for a dimension b110 desktop? Thank You for any help you can provide.
drakk
The most compatible motherboard, would be a Dimension 4600 motherboard, that has an AGP graphics card slot and two SATA connectors and supports Socket 487 processors, but you would the rear I/O panel for the 4600 motherboard.
It probably would cost less to buy a used Inspiron 530 Mini Tower, that has four SATA connectors, SATA drives, a PCI Express x16 slot and supports LGA 775 processors, which would knock the socks of any Socket 487 CPU, or take Fireberd's excellent advice and build your own system
Bev.

rdunnill
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Posted May 8th, 2011 11:00
The 3000 shares the same case as the B110 and read my tagline to see what I did with mine. :) Mind you, I did change the front audio connector to standard 2X5.
Edit: an alternative is an internal SATA card, like the two-port Syba 150R I use with my 2350. (Syba also has a four port version available.) It's a lot cheaper and troublesome than a mainboard swap.